Πλοήγηση ανά Θέμα "Breast cancer"
Αποτελέσματα 1-16 από 16
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Additive enhancement of apoptosis by TRAIL and fenretinide in metastatic breast cancer cells in vitro
(2014)Successful management of metastatic breast cancer still needs better chemotherapeutic approaches. The combination of fenretinide (4-HPR), a synthetic retinoid inducing apoptosis by ROS generation, and TRAIL, a cell death ... -
Anti-cancer activity of a novel palladium(II) complex on human breast cancer cells in vitro and in vivo
(2011)Anti-cancer effects of a newly-synthesized palladium(II) complex, [Pd(sac)(terpy)](sac)center dot 4H(2)O (sac = saccharinate, and terpy = 2,2':6',2 ''-terpyridine), were tested against human breast cancer cell lines, MCF-7 ... -
Breast cancer: Follow-up with MRI after therapy
(2009)Breast cancer is the most frequent malignancy in women worldwide. The incidence and mortality rates of the disease have increased the past few years, especially in richer countries that have adopted the mammographic screening ... -
Comparison of Two Radiotherapeutic Hypofractionated Schedules in the Application of Tumor Bed Boost
(2013)The application of the tumor bed boost by using 2 different hypofractionated planning techniques permit more efficient use of resources in hospitals. The evaluation of the radiation toxicity and the efficacy of the 2 ... -
Development of a new series of aryl ureido derivatives as anticancer agents against breast cancer cells
(2010)Breast cancer is the second cause of cancer mortality worldwide in humans and half of all tumours in dogs and there is an unmet need for novel anticancer agents. I have developed a new series of aryl ureido derivatives as ... -
Dose-dense sequential adjuvant chemotherapy followed, as indicated, by trastuzumab for one year in patients with early breast cancer: first report at 5-year median follow-up of a Hellenic Cooperative Oncology Group randomized phase III trial
(2014)Background: Dose-dense sequential chemotherapy including anthracyclines and taxanes has been established in the adjuvant setting of high-risk operable breast cancer. However, the preferable taxane and optimal schedule of ... -
Evaluation of Current Prognostic and Predictive Markers in Breast Cancer: A Validation Study of Tissue Microarrays
(2013)Background: Tissue microarrays (TMAs) are an attractive alternative to analysis of whole sections (WS). For breast carcinomas, the recent recommendations for cut-offs (i.e. Ki67, H-score) have necessitated the re-evaluation ... -
The Fat Content of Small Primary Breast Cancer Interferes with Radiofrequency-Induced Thermal Ablation
(2009)Background: Radiofrequency (RF) thermal ablation is a minimally invasive technique of local mass elimination with variable efficiency. Methods: Ten patients with small primary breast cancer diagnosed preoperatively by core ... -
High resolution computed tomography findings on the lung of early breast-cancer patients treated by postoperative breast irradiation with a hypofractionated radiotherapy schedule
(2005)BACKGROUND: Hypofractionated breast radiotherapy (RT), although convenient for patients and health care systems, could have a negative impact on normal tissues such as lung. AIM: To evaluate radiation-induced lung toxicity ... -
Mitogen-inducible gene-2 (MIG2) and migfilin expression is reduced in samples of human breast cancer
(2013)Background: Cell adhesion proteins that connect each cell to neighboring cells and the extracellular matrix play a fundamental role in metastasis. Mitogen-inducible gene-2 (MIG2), is a cell-matrix adhesion protein, which ... -
Ras suppressor-1 promotes apoptosis in breast cancer cells by inhibiting PINCH-1 and activating p53-upregulated-modulator of apoptosis (PUMA); verification from metastatic breast cancer human samples
(2015)Metastasis, responsible for most deaths from breast cancer (BC), is a multistep process leading to cancer cell spread. Extracellular matrix (ECM)-related adhesion and apoptosis resistance play pivotal role in metastasis. ... -
Regulation of aromatase expression by hormones, drugs pesticides and environmental pollutants in canine mammary CMT-U27 cells
(2010)Aromatase, the enzyme that coverts testosterone to 17β-estradiol, has attracted attention lately because of its involvement in some forms of breast cancer in women. Studies are now undergoing on a variety of species to ... -
Synchronous occurrence of breast cancer and pulmonary sclerosing hemangioma: Management and review of the literature
(2013)Pulmonary sclerosing hemangioma (PSH) is a rare tumor accounting for 0.2-1% of all primary lung tumors. Simultaneous occurrence of PSH with breast cancer has very rarely been reported in the literature. We describe here a ... -
Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes
(2015)Tamoxifen is a major treatment modality for estrogen receptor positive breast cancer, but the occurrence of resistance remains a problem. Recently, obesity-related leptin has been found to interfere with tamoxifen in breast ... -
Thrombospondin-1 expression in breast cancer: prognostic significance and association with p53 alterations, tumour angiogenesis and extracellular matrix components
(2012)Thrombospondin (TSP-1) is a 450-kd adhesive glycoprotein that was initially discovered in platelets and subsequently in a variety of cell types. Several reports suggest that TSP-1 possesses tumour suppressor function, ... -
The use of radiobiological parameters and the evaluation of NTCP models. How do they affect the ability to estimate radiation induced complications?
(2009)Normal Tissue Complication Probability (NTCP) models currently used, provide a simplified representation of the clinical radiobiology since there are number of radiobiological mechanisms which affect the clinical outcome ...